Prevalence, Sensitivity Profile and Resistance of Gram-Positive Bacteria in Wounds to Conventional Antibiotics

Alabi, Mercy and Bayode, Michael and Aina, Ikeoluwa and Adesanya, Jeremiah and Areo, Oluwaseun (2021) Prevalence, Sensitivity Profile and Resistance of Gram-Positive Bacteria in Wounds to Conventional Antibiotics. International Journal of Pathogen Research, 7 (2). pp. 9-17. ISSN 2582-3876

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Abstract

Aim: The prevalence, sensitivity profile and resistance of Gram-positive bacteria in wounds to commercial antibiotics were ascertained in this study.

Place and duration of study: University of Medical Sciences Teaching Hospital, Akure, Nigeria, between January and June 2019.

Methodology: Wound swabs sample collection, isolation of bacteria, identification of Gram-positive bacteria isolates and antibiotics sensitivity testing of isolated bacteria were determined employing standard protocols.

Result: Three Gram-positive bacteria were isolated and presumptively identified to be S. aureus, S. epidermidis and S. pyogenes. S. aureus had the highest prevalence of 53% followed by S. epidermidis with 42% and S. pyogenes accounting for the least occurrence of 5%. Ninety percent (90%) of ten S. aureus strains were resistant to ciprofloxacin while only 10% had intermediate activity. The least resistance of S. aureus strains was against pefloxacin (40%), while to streptomycin, 87.5% of eight S. epidermidis strains were resistant and 12.5% had intermediate sensitivity. Susceptibility was observed in S. epidermidis against pefloxacin (12.5%) while 50% had intermediate sensitivity and 37.5% were resistant. The highest zone of inhibition of S. epidermidis was observed in strain 7 against pefloxacin (16.00±1.00 mm) and in S. aureus by strain 5 against pefloxacin (16.50±2.50 mm).

Conclusion: Pefloxacin-sensitive Staphylococcus and Streptococcus species from wound swabs could become resistant overtime and this calls for incessant vigilance on Gram-positive wound bacteria antibiotic-susceptibility appraisal particularly in an antibiotics-abuse setting.

Item Type: Article
Subjects: Archive Paper Guardians > Biological Science
Depositing User: Unnamed user with email support@archive.paperguardians.com
Date Deposited: 21 Jan 2023 08:01
Last Modified: 11 Sep 2023 11:07
URI: http://archives.articleproms.com/id/eprint/44

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