Mishra, Shivani and Jaiswal, Saumya and Shreya, Smriti and Jain, Buddhi Prakash (2023) Post Transcriptional Gene Regulation in Breast Cancer. In: Socio-Scientific Interaction in Diabetes and Cancer and Its Management. B P International, pp. 346-370. ISBN 978-81-968135-0-5
Full text not available from this repository.Abstract
Post-transcriptional gene regulation plays an important role in the development and progression of breast cancer. It occurs after the transcription of DNA into RNA but before the synthesis of functional proteins. Breast cancer is the most common and lethal cancer that affects women worldwide. Several mechanisms involved in post-transcription are RNA binding proteins (RBP), microRNA (miRNA), alternative splicing, RNA editing, and modulation of mRNA stability. They are dysregulated in breast cancer contributing to the cell proliferation and metastasis in breast cancer. Aberrant splicing events are involved in breast cancer progression and therapeutic resistance. This chapter is an overview of post-transcriptional gene regulation and its role in breast cancer.
Item Type: | Book Section |
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Subjects: | Archive Paper Guardians > Medical Science |
Depositing User: | Unnamed user with email support@archive.paperguardians.com |
Date Deposited: | 12 Dec 2023 10:10 |
Last Modified: | 12 Dec 2023 10:10 |
URI: | http://archives.articleproms.com/id/eprint/2517 |