In vitro Evaluation of Antimicrobial Activity of Nigella sativa against Methicillin Resistant Staphylococcus aureus in Shendi Town, Sudan

El-Majeed, Sundus Amer Hassan Abd and Bashir, Mazin Babekir Musa and Bulla, Haghamad Allzain and Ahmed, Alhaj Saad Mohamed and Saeed, Omran Musa Ahmed and Gorish, Babbiker Mohammed Taher and Abdelmula, Waha Ismail Yahia (2023) In vitro Evaluation of Antimicrobial Activity of Nigella sativa against Methicillin Resistant Staphylococcus aureus in Shendi Town, Sudan. International Journal of Pathogen Research, 12 (6). pp. 76-82. ISSN 2582-3876

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Abstract

Background: Augment of antibiotics resistance with development of new aggressive strains for the same disease is an international health problem. The ability of treating diseases is based on our ability to discover a new line of treatment with highly effectiveness and simple potentiality; so Herbal-Medicine is the line of choice. Traditional Arabic medicine point to the beneficial effect of Nigella sativa in curing a lot of diseases.

The Prophetic-Sunna point out that Nigella sativa has highly therapeutic properties for various diseases. Prophet Mohammed quoted as saying “There is healing in Black seed for all diseases except death”.

Methods: A cross-sectional community and hospital-based study, was done from 10 Jan-2023 to 31 March-2023 in Shendi Town, River Nile State. 95 nasal and skin swabs were collected from people and a variety of hospitals in shendi town, then cultured on Manitol Salt Agar (MSA) for selectivity of S.aureus to be isolated, bacterial identification done by colonial morphology, Gram`s stain and biochemical tests. The antimicrobial susceptibility of S.aureus to N. sativa was carried out using agar well diffusion method.

Results: 48 pure culture of Methicillin resistant Staphylococcus aureus bacteria (MRSA) was isolated from 95 different clinical swabs specimens. Nigella sativa oil shows an effective inhibitory reactions against all MRSA bacterial isolates. All tested concentrations (50%, 25%, 13%) compared with Methicillin antibiotic inhibit 48(100%) of MRSA isolated bacteria.

Item Type: Article
Subjects: Archive Paper Guardians > Biological Science
Depositing User: Unnamed user with email support@archive.paperguardians.com
Date Deposited: 25 Nov 2023 10:30
Last Modified: 25 Nov 2023 10:30
URI: http://archives.articleproms.com/id/eprint/2375

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