Isolated intracranial Rosai-Dorfman disease in an adult man: Report of a rare case

Rezaei, Somaye and Zarzanalivan, Fariba and Pirouti, Pouya and Amiri Nikpour, Mohammad Reza and Javadi, Abdolreza and Torkamandi, Shahram (2020) Isolated intracranial Rosai-Dorfman disease in an adult man: Report of a rare case. Journal of Research in Clinical Medicine, 8 (1). p. 18. ISSN 2717-0616

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Official URL: https://doi.org/10.34172/jrcm.2020.18

Abstract

Background: Isolated intracranial Rosai-Dorfman disease (RDD) is an extremely rare, idiopathic histo-proliferative disorder. RDD is associated with the proliferation of histiocytes and emperipolesis.

Case Presentation: we report a case with isolated intracranial RDD. A 47-year- old man presented with a dizziness, falling, and then secondary generalized seizure, hemiparesis and right hemisensory deficit. This case preoperatively was misdiagnosed with meningioma. Histopathological examination revealed pale histiocytes displaying emperipolesis which were positive for S-100 and CD68 proteins and negative for CD1a marker. BRAF V600E mutation was negative.

Conclusion: In this case, total resection was performed and clinical symptoms were regressed completely.

Item Type:	Article
Subjects:	Archive Paper Guardians > Medical Science
Depositing User:	Unnamed user with email support@archive.paperguardians.com
Date Deposited:	09 Feb 2023 09:11
Last Modified:	19 Sep 2023 07:45
URI:	http://archives.articleproms.com/id/eprint/19

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