Determination of Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab, India

The male genital system consists of prostate, seminal vesicle, testes, epididymis, vas deferens, bulbourethral gland, ejaculatory duct, penis and scrotum. Male genital cancers are histologically diverse. They are difficult to detect and treat because of their anatomic locations, biological characteristics and complications. To study the histopathological spectrum of tumours of the male genital system according to World Health Organisation (WHO) classification. The present study is a hospital-based descriptive study conducted in the Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India, from February 2019 to August 2020, included 128 cases. All biopsies, specimens and blocks for review and slides of male genital tract tumours were processed and slide stained with Haematoxylin and Eosin (H&E) stain. Also used were serum tumour markers and immunohistochemical stains. The clinical information from the requisition form related to the male genital system, histopathological findings and diagnosis were recorded on the predesigned proforma. The association between categorical variables was determined using Pearson’s Chi-square test. A p-value <0.05 was considered statistically significant for this study. The present study included 128 cases, of which the majority of the cases 82 (64%) were that of the prostate, 28 case (21.9%) of the penis, 15 case (11.7%) of testes, 2 case (1.6%) were that of the scrotum and 1 case (0.8%) was of the epididymis. Prostate tumours outnumbered all other tumours of the male genital tract comprising adenocarcinoma of the prostate followed by squamous cell carcinoma of the penis and mixed Germ Cell Tumour (GCT) of the testes. The present study provides updated information regarding the histopathological spectrum of male genital system tumours.